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API STD 521: Guide for Pressure-relieving and Depressuring Systems – Edition 6

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682

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ISO 19290:2021

ISO 19290:2021 Cigarettes – Determination of tobacco specific nitrosamines in mainstream cigarette smoke – Method using LC-MS/MS

CDN $186.00

SKU: d9b6ac92257d Category:

Description

This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in the total particulate matter of mainstream cigarette smoke by using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

Edition

2

Published Date

2021-02-03

Status

PUBLISHED

Pages

14

Language Detail Icon

English

Format Secure Icon

Secure PDF

Abstract

This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in the total particulate matter of mainstream cigarette smoke by using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

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